Dupre was a third-round (27th overall) selection in the 1955 NFL Draft, played with the Baltimore Colts from 1955-59 and won two NFL championships. As a rookie he was second on the team in rushing, registering 88 carries for 338 yards, with most of his production coming after the fifth game. The next year with the addition of rookie Lenny Moore, he was forced to develop into a receiver out of the backfield and was third on the team with 216 receiving yards. His production would decrease in the following seasons, with Moore taking a bigger role in the offense. He also was a part time punter.
He was a part of the 1958 NFL Championship Game against the New York Giants, famously known as "The Greatest Game Ever Played". He started the game by gaining 30 yards on 10 carries. In 1959, Dupre played in only the first 4 regular games of the season. His only touchdown was a 2 yard pass from John Unitas against the Chicago Bears on October 18, 1959. Dupre was a member of the 1959 Baltimore Colts championship team, but due to his season-ending injury he sustained while driving home from practice, he did not play in the rematch against the Giants, which the Colts won 31-16.
He was selected by the Dallas Cowboys in the 1960 NFL Expansion Draft. In the Cowboys 1960 inaugural season, he led the team in rushing with 104 carries for 362 yards in 11 games. He also scored 3 touchdowns in the tie against the New York Giants, helping avoid losing all of the games in the season. He was released on September 4, 1962, retired from the sport and began working at General Electric in Dallas, Texas. On August 9, 2001, he died after a lengthy battle with cancer.
29° 31.039, -095° 07.453
Forest Park East Cemetery