From his ministry in Galveston Murphy worked diligently toward the annexation of Texas to the United States. When, in February 1844, annexation appeared imminent, Murphy, without authorization from his government, acceded to President Sam Houston's request for United States warships to patrol the Gulf of Mexico to protect Texas ports and harbors. For this action the chargé received the reprimand of his superiors and was given to understand that his appointment would not be confirmed by the Senate. This report caused Houston to write to Murphy on March 30, 1844, of his "regret that anything should at this time withdraw you from this Government, until the work which you have been instrumental in commencing should be terminated either by annexation, or rejection of Texas by the U[nited] States." The treaty of annexation, signed by the Texas government on April 11, 1844, was rejected by the United States Senate, and Murphy was recalled to Washington. "The tail went with the hide," as he summed up the situation. Murphy died of yellow fever in Galveston only a few weeks later, on July 12, 1844, and was buried there the following day. He was the third United States minister to Texas to die at his post since 1840.
29° 17.613, -094° 48.672
Trinity Episcopal Cemetery